Source: ASTP/ONC
The Interoperability Standards Advisory (ISA) process represents the model by which the Assistant Secretary for Technology Policy/Office of the National Coordinator (ASTP/ONC) coordinates the identification, assessment, and public awareness of interoperability standards and implementation specifications that can be used by the healthcare industry to address specific interoperability needs including, but not limited to, interoperability for clinical, public health, research and administrative purposes. ASTP/ONC encourages all stakeholders to implement and use the standards and implementation specifications identified in the ISA as applicable to the specific interoperability needs they seek to address. Furthermore, ASTP/ONC encourages further pilot testing and industry experience to be sought with respect to standards and implementation specifications identified as “emerging” in the ISA.
The 2026 ISA Reference Edition reflects the numerous changes made across the ISA throughout 2025. To learn more about updates from previous editions, refer to the Recent ISA Updates page, which provides a summary of major changes to the ISA.
